A structural and thermodynamic escape mechanism from a drug resistant mutation of the HIV-1 protease

Author:

Vega Sonia,Kang Lin-Woo,Velazquez-Campoy Adrian,Kiso Yoshiaki,Amzel L. Mario,Freire Ernesto

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

Reference31 articles.

1. Selection of multiple human immunodeficiency virus type 1 variants that encode viral proteases with decreased sensitivity to an inhibitor of the viral protease;Kaplan;Proc Natl Acad Sci,1994

2. Characterization of human immunodeficiency virus type 1 variants with increased resistant to a C2-symmetric protease inhibitor;Ho;J Virol,1994

3. In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors;Condra;Nature,1995

4. Drug-resistance patterns of saquinavir and other HIV proteinase inhibitors;Roberts;AIDS,1995

5. HIV protease inhibitors - resistance issues;Tisdale;Int Antiviral News,1996

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