Alcohol dehydrogenase III exacerbates liver fibrosis by enhancing stellate cell activation and suppressing natural killer cells in mice

Author:

Yi Hyon-Seung1,Lee Young-Sun1,Byun Jin-Seok2,Seo Wonhyo1,Jeong Jong-Min1,Park Ogyi3,Duester Gregg4,Haseba Takeshi5,Kim Sun Chang67,Park Keun-Gyu8,Gao Bin3,Jeong Won-Il1

Affiliation:

1. Laboratory of Liver Research; Graduate School of Medical Science and Engineering; KAIST Daejeon Republic of Korea

2. Department of Oral Medicine; School of Dentistry; Kyungpook National University; Daegu Republic of Korea

3. Laboratory of Liver Study; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health; Bethesda MD USA

4. Sanford-Burnham Medical Research Institute; La Jolla CA USA

5. Department of Legal Medicine; Nippon Medical School; Tokyo Japan

6. Intelligent Synthetic Biology Center; Daejeon Republic of Korea

7. Department of Biological Sciences; Korea Advanced Institute of Science and Technology; Daejeon Republic of Korea

8. Department of Internal Medicine; Kyungpook National University School of Medicine; Daegu Republic of Korea

Funder

the Bio & Medical Technology Development Program of the National Research Foundation funded by the Korean government

the Intelligent Synthetic Biology Center of Global Frontier Project funded by the Ministry of Science, ICT & Future Planning

The Korean Health Technology R&D Project, Ministry of Health & Welfare, Republic of Korea

the Next-Generation BioGreen 21 Program, Rural Development Administration, Republic of Korea

Publisher

Wiley

Subject

Hepatology

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