Use of Physiologically Based Pharmacokinetic Modeling to Evaluate the Impact of Chronic Kidney Disease on CYP3A4‐Mediated Metabolism of Saxagliptin-Reference-Cited by-同舟云学术

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Use of Physiologically Based Pharmacokinetic Modeling to Evaluate the Impact of Chronic Kidney Disease on CYP3A4‐Mediated Metabolism of Saxagliptin

Published:2022-04-04 Issue:8 Volume:62 Page:1018-1029
ISSN:0091-2700
Container-title:The Journal of Clinical Pharmacology
language:en
Short-container-title:The Journal of Clinical Pharma

Author:

Butrovich Morgan A.¹,Tang Weifeng²,Boulton David W.²,Nolin Thomas D.¹,Sharma Pradeep³

Affiliation:

1. Department of Pharmacy and Therapeutics University of Pittsburgh School of Pharmacy Pittsburgh Pennsylvania USA

2. Clinical Pharmacology and Quantitative Pharmacology Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca Gaithersburg Maryland USA

3. Clinical Pharmacology and Quantitative Pharmacology Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca Cambridge UK

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcph.2043

Reference40 articles.

1. Strategies for Reducing Polypharmacy and Other Medication-Related Problems in Chronic Kidney Disease

2. Polypharmacy and medication-related complications in the chronic kidney disease patient

3. Medication-related Problems in CKD

4. Adverse Drug Events in Patients with Chronic Kidney Disease Associated with Multiple Drug Interactions and Polypharmacy

5. Hepatic drug metabolism and transport in patients with kidney disease

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Chronic kidney disease and physiologically based pharmacokinetic modeling: a critical review of existing models;Expert Opinion on Drug Metabolism & Toxicology;2024-01-31

2. A physiologically based pharmacokinetic model of cefepime to predict its pharmacokinetics in healthy, pediatric and disease populations;Saudi Pharmaceutical Journal;2023-08

3. Physiologically Based Pharmacokinetic Modeling Characterizes the Drug‐Drug Interaction Between Saxagliptin and Rifampicin in Patients With Renal Impairment;The Journal of Clinical Pharmacology;2023-03-29

4. Physiologically Based Pharmacokinetic Modelling in Drug Discovery and Clinical Development: A Treatise on Concepts, Model Workflow, Credibility, Application and Regulatory Landscape;The Quintessence of Basic and Clinical Research and Scientific Publishing;2023

5. Predicting transporter mediated drug–drug interactions via static and dynamic physiologically based pharmacokinetic modeling: A comprehensive insight on where we are now and the way forward;Biopharmaceutics & Drug Disposition;2022-12-14

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