Response in a child with a BRAF V600E mutated desmoplastic infantile astrocytoma upon retreatment with vemurafenib-Reference-Cited by-同舟云学术

Response in a child with a BRAF V600E mutated desmoplastic infantile astrocytoma upon retreatment with vemurafenib

Published:2017-12-12 Issue:3 Volume:65 Page:e26893
ISSN:1545-5009
Container-title:Pediatric Blood & Cancer
language:en
Short-container-title:Pediatr Blood Cancer

Author:

van Tilburg Cornelis M.¹²³^ORCID,Selt Florian¹²³⁴,Sahm Felix³⁵⁶,Bächli Heidi⁷,Pfister Stefan M.¹²³⁸,Witt Olaf¹²³⁴,Milde Till¹²³⁴

Affiliation:

1. Department of Pediatric Hematology and Oncology; Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ); Heidelberg Germany

2. Department of Pediatric Hematology and Oncology; Heidelberg University Hospital; Heidelberg Germany

3. German Cancer Research Center (DKFZ) and German Consortium for Translational Cancer Research (DKTK); Heidelberg Germany

4. Clinical Cooperation Unit Pediatric Oncology; German Cancer Research Center (DKFZ); Heidelberg Germany

5. Department of Neuropathology; Institute of Pathology; University Hospital Heidelberg; Heidelberg Germany

6. Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK); German Cancer Research Center (DKFZ); Heidelberg Germany

7. Department of Neurosurgery; Heidelberg University Hospital; Heidelberg Germany

8. Division of Pediatric Neurooncology; German Cancer Research Center (DKFZ); Heidelberg Germany

Funder

Deutsche Kinderkrebsstiftung

Parents Initiative DLFH-Pfalz e.V

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology and Child Health

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/pbc.26893/fullpdf

Reference16 articles.

1. Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations;Flaherty;N Engl J Med,2012

2. MAPK pathway activation in pilocytic astrocytoma;Jones;Cell Mol Life Sci,2012

3. The first study of dabrafenib in pediatric patients with BRAF V600-mutant relapsed or refractory low-grade gliomas;Kieran;Ann Oncol,2016

4. Profound clinical and radiological response to BRAF inhibition in a 2-month-old diencephalic child with hypothalamic/chiasmatic glioma;Lassaletta;Pediatr Blood Cancer,2016

5. Successful retreatment of a child with a refractory brainstem ganglioglioma with vemurafenib.;Aguilera;Pediatr Blood Cancer,2016

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