Population‐based analysis of the human development index and risk factors for head and neck cancer

Author:

Chien I‐An1,Hsu Yi‐Chiung23ORCID,Tsai Chung‐Hsin4,Cheng Shih‐Ping456ORCID

Affiliation:

1. Department of Medical Education Taipei Veterans General Hospital Taipei Taiwan

2. Department of Biomedical Sciences and Engineering National Central University Taoyuan Taiwan

3. Center for Astronautical Physics and Engineering National Central University Taoyuan Taiwan

4. Department of Surgery MacKay Memorial Hospital and MacKay Medical College Taipei Taiwan

5. Institute of Biomedical Sciences MacKay Medical College New Taipei City Taiwan

6. Department of Pharmacology School of Medicine, College of Medicine, Taipei Medical University Taipei Taiwan

Abstract

AbstractBackgroundWe aimed to investigate global variations in incidence and mortality and their associations to possible risk factors for prompt cancer prevention and control.MethodsEstimates of incidence and mortality rates for six types of head and neck cancer were extracted from the GLOBOCAN 2020 database. Summary exposure values for level‐two risk factors were obtained from the Global Burden of Disease. Regression models adjusting for the human development index (HDI) were constructed to analyze correlations between age‐standardized rates and risk factors.ResultsThe incidence rates of multiple types of head and neck cancer were positively associated with HDI tiers. In addition to tobacco use and alcohol consumption, high systolic blood pressure was associated with the incidence and mortality of cancers of the salivary glands, oropharynx, hypopharynx, and larynx. Dietary risks were linked to cancers of the oropharynx, nasopharynx, and hypopharynx.ConclusionsThis comprehensive analysis provides valuable insights into possible risk factors for head and neck cancer.

Publisher

Wiley

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