Effectiveness and outcomes of endoscopic resection for superficial pharyngeal squamous cell carcinomas

Author:

Nakamura Naohiro1ORCID,Sakagami Tomofumi2,Shimizu Minaki2,Suzuki Kensuke2,Fujisawa Takuo2,Shijimaya Takuya1,Kobayashi Sanshiro1,Takahashi Yu1,Tahara Tomomitsu1,Noda Yuri3ORCID,Tsuta Koji3,Naganuma Makoto1

Affiliation:

1. Third Department of Internal Medicine, Division of Gastroenterology and Hepatology Kansai Medical University Osaka Japan

2. Department of Otolaryngology, Head and Neck Surgery Kansai Medical University Osaka Japan

3. Department of Pathology Kansai Medical University Osaka Japan

Abstract

AbstractBackgroundWith the development of endoscopic imaging, superficial pharyngeal squamous cell carcinoma can now be detected during routine endoscopy. Recently, the effectiveness of endoscopic resection for superficial pharyngeal squamous cell carcinoma have been reported.MethodsThis study had a retrospective single‐center design that included patients with superficial pharyngeal squamous cell carcinoma who underwent endoscopic resection. A total 47 patients with 53 lesions were analyzed.ResultsEn bloc and R0 resection rates were 83.0% and 56.6%. Local recurrence and cervical lymph node metastasis (CLNM) were detected in 1 and 3 patients during follow‐up. The macroscopic type 0‐I was an independent factor for CLNM. The 3‐year cumulative incidence of metachronous pharyngeal squamous cell carcinoma following endoscopic resection was 33.0%, and the 5‐year overall survival rate was 89.2%.ConclusionsEndoscopic resection is an effective treatment for superficial pharyngeal squamous cell carcinomas, and the macroscopic type 0‐I is a useful predictor of CLNM.

Publisher

Wiley

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