Inactivation of the Ketoreductase gilU Gene of the Gilvocarcin Biosynthetic Gene Cluster Yields New Analogues with Partly Improved Biological Activity-Reference-Cited by-同舟云学术

Inactivation of the Ketoreductase gilU Gene of the Gilvocarcin Biosynthetic Gene Cluster Yields New Analogues with Partly Improved Biological Activity

Published:2009-01-26 Issue:2 Volume:10 Page:278-286
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Liu Tao,Kharel Madan K.,Zhu Lili,Bright Samuel A.,Mattingly Cynthia,Adams Val R.,Rohr Jürgen

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Reference54 articles.

1. Gilvocarcins, new antitumor antibiotics. 1. Taxonomy, fermentation, isolation and biological activities.

2. Gilvocarcins, new antitumor antibiotics. 2. Structural elucidation.

3. Antitumor agents from Streptomyces anandii: gilvocarcins V, M and E.

4. The Complete Gene Cluster of the Antitumor Agent Gilvocarcin V and Its Implication for the Biosynthesis of the Gilvocarcins

5. New antitumor substances, BE-12406A and BE-12406B, produced by a streptomycete. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties.

Cited by 28 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Efficient synthesis of 2-benzofuranyl C -glycosides by one-pot cascade reaction of sugar alkynes and substituted 2-iodophenols;Journal of Carbohydrate Chemistry;2023-12-10

2. Ravidomycin Analogs from Streptomyces sp. Exhibit Altered Antimicrobial and Cytotoxic Selectivity;Journal of Natural Products;2023-08-02

3. Engineering BioBricks for Deoxysugar Biosynthesis and Generation of New Tetracenomycins;ACS Omega;2023-06-01

4. Post-PKS enzyme complexes;MedChemComm;2019

5. The functional differentiation of the post-PKS tailoring oxygenases contributed to the chemical diversities of atypical angucyclines;Synthetic and Systems Biotechnology;2018-12