Myocardial work in idiopathic premature ventricular contractions: Assessing left ventricular function and prognosis

Author:

Zhou Chunrui1,He Qian1,Ding Yunchuan123,Wang Qinghui123,Xian Lini1,Peng Xin1,Mao Fuyong1,Luo Qingqing1,Yang Zefan1,Yang Ping1,Chen Jian123

Affiliation:

1. Department of Ultrasound, Yanan Hospital of Kunming City The Affiliated Hospital of Kunming Medical University Kunming Yunnan China

2. Clinical Research Center of Cardiovascular Ultrasound Yunnan China

3. Yunnan Province Key Laboratory of Cardiovascular Diseases Kunming Yunnan China

Abstract

AbstractBackgroundPremature ventricular contractions (PVCs) can lead to impairment of left ventricular function. The noninvasive myocardial work technique, which incorporates left ventricular afterload, represents a new method for assessing left ventricular functional.AimThe aim of this study is to explore the value of noninvasive myocardial work technique in assessing left ventricular systolic function in patients with PVCs.MethodsCompare the clinical data, two‐dimensional echocardiography parameters, and myocardial work parameters of 66 patients with PVCs and 35 healthy volunteers and explore the relevant risk factors for postoperative recurrence in patients with PVCs.ResultsIn patients with PVCs compared to the control group, they exhibit enlargement of left atrial diameter (LAD) and left ventricular internal dimension in diastole (LVIDd), as well as thickening of the left ventricular wall. The global work waste (GWW) increases, while the global work efficiency (GWE) decreases. There is a significant negative correlation between the PVC burden and GWE (r = −0.70, p <0.01), and a significant positive correlation between the PVC burden and GWW (r = 0.58, p <0.01). GWE is a sensitive indicator for predicting the recurrence of PVCs after radiofrequency ablation. Patients with GWE <91.5%, global longitudinal strain (GLS) <15.5%, and ejection fraction (EF) <62.5% have a higher postoperative recurrence rate.ConclusionPVCs can cause impairment of left ventricular systolic function. GWE is the most sensitive indicator for predicting postoperative recurrence in patients with PVCs. Patients with GWE <91.5%, GLS <15.5%, and EF <62.5% have a higher postoperative recurrence rate.

Publisher

Wiley

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