Persistence of a Posaconazole-Mediated Drug-Drug Interaction With Ranolazine After Cessation of Posaconazole Administration: Impact of Obesity and Implications for Patient Safety

Author:

Chow Christina R.1ORCID,Harmatz Jerold S.2,Ryan Michael J.1,Greenblatt David J.2

Affiliation:

1. Emerald Lake Safety LLC; Newport Beach CA USA

2. Tufts University School of Medicine; Boston MA USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference25 articles.

1. Obesity: preventing and managing the global epidemic: report of a WHO consultation;World Health Organization (WHO);WHO Tech Rep Ser,2000

2. Heart disease and stroke statistics-2016 update a report from the American Heart Association;Mozaffarian;Circulation,2016

3. Prescription medication use among normal weight, overweight, and obese adults, United States, 2005-2008;Kit;Ann Epidemiol,2012

4. U.S. Department of Health and Human Services, Food and Drug Administration Guidance for Industry. E14 Clinical Evaluation of QT/QTc Interval Prolongation and Proarrhythmic Potential for Non-Antiarrhythmic Drugs https://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM073153.pdf 2018

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