Metabolic activation of 3-methylcholanthrene and benzo(a)pyrene to mutagens in the L5178Y/TK assay by cultured embryonic rodent cells
Author:
Publisher
Wiley
Subject
Health, Toxicology and Mutagenesis,Genetics
Reference34 articles.
1. Induction of trifluorothymidine-resistant mutants by metal ions in L5178Y/TK+/− cells
2. Trifluorothymidine resistance and colony size in L5178y/TK+/? cells treated with methyl methanesulfonate
3. Point mutations at the thymidine kinase locus in L5178Y mouse lymphoma cells II. Test validation and interpretation
4. Point mutations at the thymidine kinase locus in L5178Y mouse lymphoma cells
5. Promutagen activation by rodent-liver postmitochondrial fractions in the L5178Y/TK cell mutation assay
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1. Genetic Toxicology Testing and its Relevance to Human Risk and Safety Evaluation;General and Applied Toxicology;2009-12-15
2. Mutant yields and mutational spectra of the heterocyclic amines MeIQ and PhIP at the S1 locus of human-hamster AL cells with activation by chick embryo liver (CELC) co-cultures;Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis;1999-03
3. The Use of Intact Mammalian Cells as Metabolic Activation Systems in Mutagenicity Tests;Advances in Mutagenesis Research;1990
4. Studies of an S9-based metabolic activation system used in the mouse lymphoma L5178Y cell mutation assay;Mutagenesis;1988
5. Comparison of mutagenicities in asalmonella reversion assay mediated by uninduced hepatocytes and hepatocytes from rats pretreated for 1 or 5 days with aroclor 1254;Environmental Mutagenesis;1985
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