A multi-analyte approach to help in assessing the severity of acute poisonings - Development and validation of a fast LC-MS/MS quantification approach for 45 drugs and their relevant metabolites with one-point calibration

Author:

Michely Julian A.1ORCID,Maurer Hans H.1ORCID

Affiliation:

1. Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology; Saarland University; Homburg Germany

Publisher

Wiley

Subject

Spectroscopy,Pharmaceutical Science,Environmental Chemistry,Analytical Chemistry

Reference37 articles.

1. Demands on scientific studies in clinical toxicology;Maurer;Forensic Sci Int,2007

2. Development and validation of a fast and simple multi-analyte procedure for quantification of 40 drugs relevant to emergency toxicology using GC-MS and one-point calibration;Meyer;Drug Test Anal,2014

3. Automated mass spectral deconvolution and identification system for GC-MS screening for drugs, poisons, and metabolites in urine;Meyer;Clin Chem,2010

4. Development of the first metabolite-based LC-MS(n) urine drug screening procedure-exemplified for antidepressants;Wissenbach;Anal Bioanal Chem,2011

5. Orbitrap technology for comprehensive metabolite-based liquid chromatographic-high resolution-tandem mass spectrometric urine drug screening - exemplified for cardiovascular drugs;Helfer;Anal Chim Acta,2015

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