Continuous bind-and-elute protein A capture chromatography: Optimization under process scale column constraints and comparison to batch operation
Author:
Affiliation:
1. Dept. of Purification Process Development; Amgen Inc., One Amgen Center Drive; Thousand Oaks CA 91320
Publisher
Wiley
Subject
Biotechnology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/btpr.2291/fullpdf
Reference26 articles.
1. Riske F Godawat R Brower K Lacki KM Konstantinov K Warikoo V. 16th International Conference on Biopartitioning and Purification, BPP2011 2011
2. Periodic counter-current chromatography - design and operational considerations for integrated and continuous purification of proteins;Godawat;Biotechnol J.,2012
3. Integrated continuous production of recombinant therapeutic proteins;Warikoo;Biotechnol Bioeng.,2012
4. Purification of monoclonal antibodies from clarified cell culture fluid using Protein A capture continuous countercurrent tangential chromatography;Dutta;J Biotechnol.,2015
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