Novel Protein Biomarkers of Monoamine Metabolism Defects Correlate with Disease Severity

Author:

Tristán‐Noguero Alba1,Borràs Eva2,Molero‐Luis Marta3,Wassenberg Tessa4,Peters Tessa4,Verbeek Marcel M.45,Willemsen Michel6,Opladen Thomas7,Jeltsch Kathrin7,Pons Roser8,Thony Beat9,Horvath Gabriella10,Yapici Zuhal11,Friedman Jennifer1213,Hyland Keith14,Agosta Guillermo E.15,López‐Laso Eduardo16,Artuch Rafael3,Sabidó Eduard2,García‐Cazorla Àngels117

Affiliation:

1. Synaptic Metabolism Laboratory, Sant Joan de Déu Foundation, Research Pediatric Institute (IPR), Sant Joan de Déu Hospital Barcelona Spain

2. Proteomics Unit Center for Genomics Regulation, Barcelona Institute of Science and Technology Barcelona Spain

3. Department of Clinical Biochemistry IPR and CIBERER‐ISCIII, Sant Joan de Déu Hospital Barcelona Spain

4. Department of Neurology Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour Nijmegen the Netherlands

5. Department of Pediatric Neurology Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour Nijmegen the Netherlands

6. Department Laboratory Medicine Radboud University Medical Center Nijmegen the Netherlands

7. Division of Neuropediatrics & Metabolic Medicine University Children's Hospital Heidelberg Germany

8. First Department of Pediatrics, Pediatric Neurology Unit Agia Sofia Hospital, National and Kapodistrian University of Athens Athens Greece

9. Division of Metabolism and Children's Research Centre University Children's Hospital Zurich Switzerland

10. Department of Pediatrics University of British Columbia Vancouver Canada

11. Division of Child Neurology, Department of Neurology Istanbul University, Istanbul Faculty of Medicine Istanbul Turkey

12. Departments of Neuroscience and Pediatrics, University of California San Diego California USA

13. Rady Children's Hospital and Rady Children's Institute for Genomic Medicine San Diego California USA

14. Medical Neurogenetics, LLC Atlanta Georgia USA

15. Hospital Italiano de Buenos Aires Buenos Aires Argentina

16. Pediatric Neurology Unit, Department of Pediatrics University Hospital Reina Sofía, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), and CIBERER Córdoba Spain

17. Neurometabolic Unit, Neurology Department IPR, CIBER ("Centro de investigación Biomédica en Red”) of Rare Diseases and Carlos III Healthcare Institute (CIBERER‐ISCIII), European Reference Network for Hereditary Metabolic Disorders (MetabERN), Sant Joan de Déu Hospital Barcelona Spain

Funder

Instituto de Salud Carlos III

Publisher

Wiley

Subject

Neurology (clinical),Neurology

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