Two Triterpene Synthases from Imperata cylindrica Catalyzing the Formation of a Pair of Diastereoisomers through Boat or Chair Cyclization-Reference-Cited by-同舟云学术

Two Triterpene Synthases from Imperata cylindrica Catalyzing the Formation of a Pair of Diastereoisomers through Boat or Chair Cyclization

Published:2021-04-07 Issue:11 Volume:22 Page:1992-2001
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Naraki Shingo¹,Kakihara Mai¹,Kato Sayuri¹,Saga Yusuke¹,Mannen Kazuto²,Takase Shohei¹,Takano Akihito³,Shinpo Sayaka²,Hosouchi Tsutomu²,Nakane Takahisa³,Suzuki Hideyuki²,Kushiro Tetsuo¹^ORCID

Affiliation:

1. School of Agriculture Meiji University 1-1-1 Higashimita, Tama-ku Kawasaki Kanagawa 214-8571 Japan

2. Kazusa DNA Research Institute 2-6-7 Kazusa-kamatari Kisarazu Chiba 292-0818 Japan

3. Faculty of Pharmaceutical Sciences Showa Pharmaceutical University 3-3165 Higashitamagawagakuen Machida Tokyo 194-8543 Japan

Funder

Meiji University

Japan Society for the Promotion of Science

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbic.202100077

Reference35 articles.

1. Triterpenes

2. On the origins of triterpenoid skeletal diversity

3. The methyl group at C(10) of 2,3-oxidosqualene is crucial to the correct folding of this substrate in the cyclization-rearrangement step of sterol biosynthesis

4. Lanosterol Biosynthesis: The Critical Role of the Methyl-29 Group of 2,3-Oxidosqualene for the Correct Folding of this Substrate and for the Construction of the Five-Membered D Ring

5. Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase

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