Developments in siRNA Modification and Ligand Conjugated Delivery To Enhance RNA Interference Ability
Author:
Affiliation:
1. Bioorganic Chemistry Laboratory Graduate School of Science Nagoya University Chikusa-ku Nagoya Aichi 464-0813 Japan
2. Bioorganic Chemistry Laboratory Graduate School of Science Nagoya University Chikusa-Ku Nagoya Aichi 464-8602 Japan
Funder
Japan Agency for Medical Research and Development
Japan Science and Technology Agency
Publisher
Wiley
Subject
Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbic.202000009
Reference60 articles.
1. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
2. siRNA-nanoparticle conjugate in gene silencing: A future cure to deadly diseases?
3. Overcoming cellular barriers for RNA therapeutics
4. Lipid-based vectors for siRNA delivery
5. U.S. Food and Drug Administration 2019 https://www.fda.gov/news-events/press-announcements/fda-approves-first-its-kind-targeted-rna-based-therapy-treat-rare-disease (assessed November 2019).
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