Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine Methyltransferase-Reference-Cited by-同舟云学术

Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine Methyltransferase

Published:2021-02-11 Issue:9 Volume:22 Page:1597-1608
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Talibov Vladimir O.¹^ORCID,Fabini Edoardo²³^ORCID,FitzGerald Edward A.¹⁴^ORCID,Tedesco Daniele²³^ORCID,Cederfeldt Daniela¹,Talu Martin J.¹,Rachman Moira M.⁵^ORCID,Mihalic Filip¹,Manoni Elisabetta³,Naldi Marina²⁶^ORCID,Sanese Paola⁷,Forte Giovanna⁷,Lepore Signorile Martina⁷,Barril Xavier⁵⁸,Simone Cristiano⁷⁹,Bartolini Manuela²^ORCID,Dobritzsch Doreen¹,Del Rio Alberto³¹⁰^ORCID,Danielson U. Helena¹¹¹^ORCID

Affiliation:

1. Department of Chemistry–BMC Uppsala University Husargatan 3 754 24 Uppsala Sweden

2. Department of Pharmacy and Biotechnology Alma Mater Studiorum University of Bologna Via Belmeloro 6 40126 Bologna Italy

3. Institute for Organic Synthesis and Photoreactivity National Research Council Via P. Gobetti 101 40129 Bologna Italy

4. Beactica Therapeutics AB Virdings allé 2 754 50 Uppsala Sweden

5. Institut de Biomedicina de la Universitat de Barcelona (IBUB) and Facultat de Farmacia Universitat de Barcelona Av. Joan XXIII 27–31 08028 Barcelona Spain

6. Centre for Applied Biomedical Research Alma Mater Studiorum University of Bologna Via Zamboni, 33 Bologna 40126 Italy

7. Medical Genetics, National Institute for Gastroenterology IRCCS ‘S. de Bellis' Research Hospital 70013 Bari Italy

8. Catalan Institution for Research and Advanced Studies (ICREA) Passeig Lluis Companys 23 08010 Barcelona Spain

9. Medical Genetics, Department of Biomedical Sciences and Human Oncology (DIMO) University of Bari Aldo Moro 70124 Bari Italy

10. Innovamol Consulting Srl Via Giardini 470/H 41124 Modena Italy

11. Science for Life Laboratory Uppsala University Uppsala 752 37 Sweden

Funder

Regione Emilia-Romagna

Ministero della Salute

H2020 Marie Skłodowska-Curie Actions

Vetenskapsrådet

Publisher