Affiliation:
1. School of Food and Biological Engineering Hefei University of Technology Hefei Anhui 230009 China
2. Department of Chemistry University of Science and Technology of China Hefei 230026 China
Abstract
AbstractProtein post‐translational modifications (PTMs) regulate nearly all biological processes in eukaryotic cells, and synthetic PTM protein tools are widely used to detect the activity of the related enzymes and identify the interacting proteins in cell lysates. Recently, the study of these enzymes and the interacting proteome has been accomplished in live cells using cell‐permeable PTM protein tools. In this concept, we will introduce cell penetrating techniques, the syntheses of cell‐permeable PTM protein tools, and offer some future perspective.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Anhui Province
Subject
Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry
Cited by
2 articles.
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