Increased Valency Improves Inhibitory Activity of Peptides Targeting Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)-Reference-Cited by-同舟云学术

Increased Valency Improves Inhibitory Activity of Peptides Targeting Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)

Published:2021-04-28 Issue:12 Volume:22 Page:2154-2160
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Tombling Benjamin J.¹^ORCID,Lammi Carmen²,Bollati Carlotta²,Anoldi Anna²,Craik David J.¹^ORCID,Wang Conan K.¹^ORCID

Affiliation:

1. Institute for Molecular Bioscience Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science The University of Queensland Brisbane Qld, 4072 Australia

2. Dipartimento di Scienze Farmaceutiche Università degli Studi di Milano Via L. Mangiagalli 25 20133 Milan Italy

Funder

National Health and Medical Research Council

Australian Research Council

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbic.202100103

Reference56 articles.

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4. Molecular genetics of the LDL receptor gene in familial hypercholesterolemia

5. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

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