Strong and Specific Recognition of CAG/CTG Repeat DNA (5’‐dWGCWGCW‐3’) by a Cyclic Pyrrole‐Imidazole Polyamide-Reference-Cited by-同舟云学术

Strong and Specific Recognition of CAG/CTG Repeat DNA (5’‐dWGCWGCW‐3’) by a Cyclic Pyrrole‐Imidazole Polyamide

Published:2021-11-18 Issue:2 Volume:23 Page:
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Hirose Yuki¹,Ohno Tomo¹,Asamitsu Sefan¹²,Hashiya Kaori¹,Bando Toshikazu¹,Sugiyama Hiroshi¹³^ORCID

Affiliation:

1. Department of Chemistry Graduate School of Science Kyoto University Kitashirakawa-oiwakecho Sakyo-ku Kyoto 606-8502 Japan

2. Present address: Department of Genomic Neurology Institute of Molecular Embryology and Genetics Kumamoto University, Honjo Chuo-ku Kumamoto 860-0811 Japan

3. Institute for Integrated Cell-Material Science (iCeMS) Kyoto University, Yoshida-ushinomiyacho Sakyo-ku, countryPart/>Kyoto 606-8501 Japan

Funder

Japan Agency for Medical Research and Development

National Institutes of Health

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbic.202100533

Reference22 articles.

1. Expandable DNA repeats and human disease

2. DNA repeat expansions and human disease

3. Reversal of RNA Dominance by Displacement of Protein Sequestered on Triplet Repeat RNA

4. Covalent Small-Molecule-RNA Complex Formation Enables Cellular Profiling of Small-Molecule-RNA Interactions

5. Covalent Small-Molecule-RNA Complex Formation Enables Cellular Profiling of Small-Molecule-RNA Interactions

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3. A cyclic pyrrole-imidazole polyamide reduces pathogenic RNA in CAG/CTG triplet repeat neurological disease models;Journal of Clinical Investigation;2023-11-15

4. Pyrrole–Imidazole Polyamides – A Frontrunner in Nucleic Acid‐Based Small Molecule Drugs;Advanced Therapeutics;2023-03-25

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