A reporter cell system for the triggering receptor expressed on myeloid cells 2 reveals differential effects of disease‐associated variants on receptor signaling and activation by antibodies against the stalk region-Reference-Cited by-同舟云学术

A reporter cell system for the triggering receptor expressed on myeloid cells 2 reveals differential effects of disease‐associated variants on receptor signaling and activation by antibodies against the stalk region

Published:2020-12-14 Issue:5 Volume:69 Page:1126-1139
ISSN:0894-1491
Container-title:Glia
language:en
Short-container-title:Glia

Author:

Ibach Melanie¹,Mathews Mona²,Linnartz‐Gerlach Bettina³,Theil Sandra¹,Kumar Sathish¹,Feederle Regina⁴⁵,Brüstle Oliver²⁶,Neumann Harald³^ORCID,Walter Jochen¹^ORCID

Affiliation:

1. Department of Neurology University of Bonn Bonn Germany

2. Life and Brain GmbH Bonn Germany

3. Neural Regeneration, Institute of Reconstructive Neurobiology University of Bonn Medical Faculty & University Hospital Bonn Bonn Germany

4. Institute for Diabetes and Obesity, Monoclonal Antibody Core Facility, Helmholtz Zentrum München, German Research Center for Environmental Health Neuherberg Germany

5. Core Facility Monoclonal Antibodies, German Center for Neurodegenerative Diseases (DZNE) Munich Germany

6. Institute of Reconstructive Neurobiology University of Bonn Medical Faculty & University Hospital Bonn Bonn Germany

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/glia.23953

Reference57 articles.

1. The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44

2. Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)

3. Cargo Capture and Bulk Flow in the Early Secretory Pathway