The serotonin 2B receptor is required in neonatal microglia to limit neuroinflammation and sickness behavior in adulthood

Author:

Béchade Catherine123ORCID,D'Andrea Ivana123,Etienne Fanny123,Verdonk Franck4ORCID,Moutkine Imane123,Banas Sophie M.123,Kolodziejczak Marta123,Diaz Silvina L.123,Parkhurst Christopher N.5ORCID,Gan Wenbiao B.5,Maroteaux Luc123ORCID,Roumier Anne123ORCID

Affiliation:

1. INSERM UMR‐S 1270 Paris France

2. Sorbonne Université, Faculté des Sciences et Ingénierie Paris France

3. Institut du Fer à Moulin Paris France

4. Experimental Neuropathology, Infection and Epidemiology Department Institut Pasteur Paris France

5. Molecular Neurobiology Program, The Kimmel Center for Biology and Medicine at the Skirball Institute, Department of Neuroscience and Physiology New York University School of Medicine New York New York USA

Funder

Agence Nationale de la Recherche

Fédération pour la Recherche sur le Cerveau

Fondation de France

Fondation pour la Recherche Médicale

Centre National de la Recherche Scientifique

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Neurology

Reference69 articles.

1. Genetic deletion of xCT attenuates peripheral and central inflammation and mitigates LPS‐induced sickness and depressive‐like behavior in mice;Albertini G.;Glia,2018

2. Early-Life Blockade of the 5-HT Transporter Alters Emotional Behavior in Adult Mice

3. A Dialogue between the Immune System and Brain, Spoken in the Language of Serotonin

4. Positive regulation of raphe serotonin neurons by serotonin 2B receptors

5. A population‐specific HTR2B stop codon predisposes to severe impulsivity;Bevilacqua L.;Nature,2010

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