Population‐based discovery and Mendelian randomization analysis identify telmisartan as a candidate medicine for Alzheimer's disease in African Americans

Author:

Zhang Pengyue1,Hou Yuan2,Tu Wanzhu1,Campbell Noll3,Pieper Andrew A.45678,Leverenz James B.910,Gao Sujuan1,Cummings Jeffrey11,Cheng Feixiong2912

Affiliation:

1. Department of Biostatistics and Health Data Science Indiana University Indianapolis Indiana USA

2. Genomic Medicine Institute Lerner Research Institute Cleveland Clinic Cleveland Ohio USA

3. Department of Pharmacy Practice Purdue University West Lafayette Indiana USA

4. Harrington Discovery Institute University Hospitals Cleveland Medical Center Cleveland Ohio USA

5. Department of Psychiatry Case Western Reserve University Cleveland Ohio USA

6. Geriatric Psychiatry GRECC Louis Stokes Cleveland VA Medical Center Cleveland Ohio USA

7. Institute for Transformative Molecular Medicine School of Medicine Case Western Reserve University Cleveland Ohio USA

8. Department of Neuroscience Case Western Reserve University School of Medicine Cleveland Ohio USA

9. Department of Molecular Medicine Cleveland Clinic Lerner College of Medicine Case Western Reserve University Cleveland Ohio USA

10. Lou Ruvo Center for Brain Health Neurological Institute Cleveland Clinic Cleveland Ohio USA

11. Chambers‐Grundy Center for Transformative Neuroscience Department of Brain Health School of Integrated Health Sciences University of Nevada Las Vegas Las Vegas Nevada USA

12. Case Comprehensive Cancer Center Case Western Reserve University School of Medicine Cleveland Ohio USA

Funder

National Institute on Aging

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

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