Caution against examining the role of reverse causality in Mendelian Randomization-Reference-Cited by-同舟云学术

Caution against examining the role of reverse causality in Mendelian Randomization

Published:2021-05-19 Issue: Volume: Page:
ISSN:0741-0395
Container-title:Genetic Epidemiology
language:en
Short-container-title:Genetic Epidemiology

Author:

Lutz Sharon M.¹²^ORCID,Wu Ann Chen¹,Hokanson John E.³,Vansteelandt Stijn⁴⁵,Lange Christoph²

Affiliation:

1. Department of Population Medicine, PRecisiOn Medicine Translational Research (PROMoTeR) Center Harvard Medical School and Harvard Pilgrim Health Care Institute Boston Massachusetts USA

2. Department of Biostatistics Harvard T. H. Chan School of Public Health Boston Massachusetts USA

3. Department of Epidemiology, Anschutz Medical Campus University of Colorado Aurora Colorado USA

4. Department of Applied Mathematics, Computer Science, and Statistics Ghent University Ghent Belgium

5. Department of Medical Statistics London School of Hygiene and Tropical Medicine London UK

Funder

National Heart, Lung, and Blood Institute

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Publisher

Wiley

Subject

Genetics(clinical),Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/gepi.22385

Reference24 articles.

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3. Mendelian Randomization with invalid instruments: Effect estimation and bias detection through Egger regression;Bowden J.;International Journal of Epidemiology,2015

4. Consistent estimation in Mendelian Randomization with some invalid instruments using a weighted median estimator;Bowden J.;Genetic Epidemiology,2016

5. Mendelian randomization analysis of case‐control data using structural mean models;Bowden J.;Statistics in Medicine,2011

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