A classifier integrating plasma biomarkers and radiological characteristics for distinguishing malignant from benign pulmonary nodules

Author:

Lin Yanli1,Leng Qixin1,Jiang Zhengran12,Guarnera Maria A.1,Zhou Yun3,Chen Xueqi4,Wang Heping5,Zhou Wenxian5,Cai Ling5,Fang HongBin5,Li Jie6,Jin Hairong6,Wang Linghui6,Yi Shaoqiong6,Lu Wei7,Evers David8,Fowle Carol B.8,Su Yun9,Jiang Feng18ORCID

Affiliation:

1. Department of Pathology; University of Maryland School of Medicine; Baltimore MD

2. The F. Edward Hébert School of Medicine at the Uniformed Services University of the Health Sciences; Bethesda MD

3. The Russell H. Morgan Department of Radiology and Radiological Science; Johns Hopkins University School of Medicine; Baltimore MD

4. Department of Nuclear Medicine; Peking University First Hospital; Beijing China

5. Department of Biostatistics, Bioinformatics and Biomathematics; Georgetown University Medical Center; WA

6. Department of Thoracic Surgery; The General Hospital of PLA; Beijing China

7. Department of Medical Physics; Memorial Sloan Kettering Cancer Center; NY

8. VA Maryland Health Care System, Baltimore VA Medical Center; Baltimore MD

9. Department of Surgery; Jiangsu Province Hospital of Traditional Chinese Medicine (TCM), Affiliated Hospital of Nanjing University of TCM; Nanjing China

Funder

National Cancer Institute

Award

Geaton, JoAnn DeCesaris Family Foundation, DoD-Idea Development Award

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference49 articles.

1. Reduced lung-cancer mortality with low-dose computed tomographic screening;Aberle;N Engl J Med,2011

2. Screening for lung cancer: US preventive services task force recommendation statement;Moyer;Ann Intern Med,2014

3. Overdiagnosis in low-dose computed tomography screening for lung cancer;Patz;JAMA Intern Med,2014

4. Solitary pulmonary nodule: detection and management;Diederich;Cancer Imaging,2006

5. The national lung screening trial: overview and study design;Aberle;Radiology,2011

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