Predicting functional significance of cancer-associated p16INK4a mutations in CDKN2A

Author:

McKenzie Heather A.,Fung Carina,Becker Therese M.,Irvine Mal,Mann Graham J.,Kefford Richard F.,Rizos Helen

Publisher

Wiley

Subject

Genetics (clinical),Genetics

Reference53 articles.

1. Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts;Alcorta;Proc Natl Acad Sci USA,1996

2. The melanoma-associated 24 base pair duplication in p16INK4a is functionally impaired;Becker;Int J Cancer,2005

3. The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a;Becker;Mol Cancer,2009

4. Functional impairment of melanoma-associated p16INK4a mutants in melanoma cells despite retention of cyclin-dependent kinase 4 binding;Becker;Clin Cancer Res,2001

5. Geographical variation in the penetrance of CDKN2A mutations for melanoma;Bishop;J Natl Cancer Inst,2002

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