Deuteration of a molecular probe for DNP hyperpolarization - a new approach and validation for choline chloride

Author:

Allouche-Arnon Hyla,Lerche Mathilde H.1,Karlsson Magnus1,Lenkinski Robert E.2,Katz-Brull Rachel

Affiliation:

1. Albeda Research; Gamle Carlsberg Vej 10; 2500; Valby; Denmark

2. Department of Radiology; Beth Israel Deaconess Medical Center and Harvard Medical School; Boston; Massachusetts; USA

Publisher

Wiley

Subject

Radiology, Nuclear Medicine and imaging

Reference37 articles.

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3. Production of hyperpolarized [1,4-C-13(2)]malate from [1,4-C-13(2)]fumarate is a marker of cell necrosis and treatment response in tumors;Gallagher;Proc Natl Acad Sci USA,2009

4. Perfusion imaging with a freely diffusible hyperpolarized contrast agent;Grant;Magn Reson Med,2011

5. In vivo detection of rat brain metabolism using hyperpolarized acetate;Mishkovsky;Proc Int Soc Mag Reson Med (Stockh),2010

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