Pharmacokinetics and pharmacodynamics of the cytolytic anti-CD38 human monoclonal antibody TAK-079 in monkey - model assisted preparation for the first in human trial
Author:
Affiliation:
1. Takeda Pharmaceuticals International AG; Zurich Switzerland
2. Takeda Pharmaceuticals International; Cambridge Massachusetts
Publisher
Wiley
Subject
General Pharmacology, Toxicology and Pharmaceutics,Neurology
Reference26 articles.
1. SLE peripheral blood B cell, T cell and myeloid cell transcriptomes display unique profiles and each subset contributes to the interferon signature;Becker;PLoS One,2013
2. B cells in rheumatoid arthritis: From pathogenic players to disease biomarkers;Bugatti;Biomed Res Int,2014
3. Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors;Weers;J Immunol,2011
Cited by 11 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Review of the Existing Translational Pharmacokinetics Modeling Approaches Specific to Monoclonal Antibodies (mAbs) to Support the First-In-Human (FIH) Dose Selection;International Journal of Molecular Sciences;2022-10-22
2. Effect of CD38 on B‐cell function and its role in the diagnosis and treatment of B‐cell‐related diseases;Journal of Cellular Physiology;2022-04-29
3. Allometric scaling of therapeutic monoclonal antibodies in preclinical and clinical settings;mAbs;2021-01-01
4. Repositioning drugs for systemic lupus erythematosus;Systemic Lupus Erythematosus;2021
5. Daratumumab and Nanobody-Based Heavy Chain Antibodies Inhibit the ADPR Cyclase but not the NAD+ Hydrolase Activity of CD38-Expressing Multiple Myeloma Cells;Cancers;2020-12-30
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3