Population Pharmacokinetic and Pharmacodynamic Modeling of AZD4901 and Simulation to Support Dose Selection for the Phase 2a Study

Author:

Xu Hongmei1,Li Jianguo1,Webber Lorraine2,Kakkar Rahul3,Chen Yingxue1,Al-Huniti Nidal1

Affiliation:

1. Quantitative Clinical Pharmacology; AstraZeneca; Waltham MA USA

2. Scientific Partnering & Alliances; Innovative Medicines; AstraZeneca Cambridge UK

3. Scientific Partnering & Alliances; Innovative Medicines; AstraZeneca Waltham MA USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

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4. Population pharmacokinetic analysis of danvatirsen supporting flat dosing switch;Journal of Pharmacokinetics and Pharmacodynamics;2019-01-19

5. Drug-disease modeling in the pharmaceutical industry - where mechanistic systems pharmacology and statistical pharmacometrics meet;European Journal of Pharmaceutical Sciences;2017-11

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