Overall survival in metastatic melanoma correlates with pembrolizumab exposure and T cell exhaustion markers
Author:
Affiliation:
1. Calvary Mater Hospital Newcastle Waratah NSW Australia
2. Centre for Drug Repurposing and Medicines Research University of Newcastle and Hunter Medical Research Institute Callaghan NSW Australia
Funder
Cancer Institute NSW
Hunter Medical Research Institute
Publisher
Wiley
Subject
General Pharmacology, Toxicology and Pharmaceutics,Neurology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.808
Reference43 articles.
1. Immune checkpoint blockade therapy for cancer: An overview of FDA-approved immune checkpoint inhibitors
2. T-cell exhaustion in the tumor microenvironment
3. National Comprehensive Cancer Network.Cutaneous melanoma (Version 4.2020).https://www.nccn.org/professionals/physician_gls/pdf/cutaneous_melanoma_blocks.pdf. Accessed October 15 2020.
4. Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
5. Clinical Pharmacokinetics and Pharmacodynamics of Immune Checkpoint Inhibitors
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