Affiliation:
1. Sorbonne Université, CNRS Institut Parisien de Chimie Moléculaire (IPCM UMR 8232) 75005 Paris France
Abstract
AbstractThe medicinal chemistry of gold has experienced an exponential development since the 2000s. For long, the mechanisms of action of gold complexes have been limited to direct coordination of the gold ion or supramolecular interactions of the whole gold complex with biomolecules. In the recent years, other modes of action of gold‐based drug candidates have emerged. Herein, we review these new modalities, including photo‐induced cytotoxicity, selective protein modification and in cellulo catalysis.
Reference142 articles.
1. The History of Gold Therapy for Tuberculosis
2. Oral gold. Antiarthritic properties of alkylphosphinegold coordination complexes
3. The side effects of platinum-based chemotherapy drugs: a review for chemists
4. “Study Record | Beta ClinicalTrials.gov ” can be found underhttps://beta.clinicaltrials.gov/study/NCT01419691 n.d.
5. “Study Record | Beta ClinicalTrials.gov ” can be found underhttps://beta.clinicaltrials.gov/study/NCT03456700 n.d.
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