A Thorough QT Study to Evaluate the Effects of a Supratherapeutic Dose of Sertraline on Cardiac Repolarization in Healthy Subjects-Reference-Cited by-同舟云学术

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A Thorough QT Study to Evaluate the Effects of a Supratherapeutic Dose of Sertraline on Cardiac Repolarization in Healthy Subjects

Published:2020-04 Issue:3 Volume:9 Page:307-320
ISSN:2160-763X
Container-title:Clinical Pharmacology in Drug Development
language:en
Short-container-title:Clinical Pharmacology in Drug Development

Author:

Abbas Richat¹,Riley Steve²,LaBadie Robert R.³,Bachinsky Mary⁴,Chappell Phillip B.⁵,Crownover Penelope H.²,Damle Bharat⁶

Affiliation:

1. Clinical PharmacologyPfizer Essential HealthPfizer Inc Collegeville Pennsylvania USA

2. Clinical PharmacologyPfizer Inc Groton Connecticut USA

3. Clinical StatisticsPfizer Inc New York New York USA

4. CNS Clinical AffairsPfizer Essential HealthPfizer Inc New York New York USA

5. CNS Clinical AffairsPfizer Essential HealthPfizer, Inc. Groton Connecticut USA

6. Clinical PharmacologyPfizer Inc New York New York USA

Funder

funded by Pfizer

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpdd.749

Reference38 articles.

1. An evidence-based review of the clinical use of sertraline in mood and anxiety disorders

3. Human Cytochromes Mediating Sertraline Biotransformation: Seeking Attribution

4. Comparison of the Effects of Sertraline and Its Metabolite Desmethylsertraline on Blockade of Central 5-HT Reuptake In Vivo

5. Pharmacokinetics of Selective Serotonin Reuptake Inhibitors: Clinical Relevance

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