Altered mitochondrial genome content signals worse pathology and prognosis in prostate cancer

Author:

Kalsbeek Anton M. F.12ORCID,Chan Eva K. F.12,Grogan Judith345,Petersen Desiree C.12,Jaratlerdsiri Weerachai1,Gupta Ruta345,Lyons Ruth J.1,Haynes Anne-Maree5,Horvath Lisa G.456,Kench James G.345ORCID,Stricker Phillip D.7,Hayes Vanessa M.1245ORCID

Affiliation:

1. Laboratory for Human Comparative and Prostate Cancer Genomics; Genomics and Epigenetics Division; Garvan Institute of Medical Research; Darlinghurst New South Wales Australia

2. School of Medical Sciences; University of New South Wales Sydney; Randwick New South Wales Australia

3. Department of Tissue Pathology and Diagnostic Oncology; Royal Prince Alfred Hospital; Camperdown New South Wales Australia

4. Central Clinical School; Sydney Medical School; University of Sydney; Camperdown New South Wales Australia

5. Cancer Research Division; The Kinghorn Cancer Center; Garvan Institute of Medical Research; Darlinghurst New South Wales Australia

6. Chris O'Brien Lifehouse; Camperdown New South Wales Australia

7. Department of Urology; St. Vincent's Hospital; Darlinghurst New South Wales Australia

Funder

Perpetual IMPACT Fund, Australia

Sydney Medical School Foundation

Prostate Cancer Foundation of Australia

Movember Australia

Petre Foundation

Australian Prostate Cancer Research Center New South Wales (APCRC-NSW)

Prostate Cancer Bone Metastasis

Movember Revolutionary Team Award

Publisher

Wiley

Subject

Urology,Oncology

Reference38 articles.

1. Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012;Ferlay;Eur J Cancer,2015

2. The 2014 international society of urological pathology (ISUP) consensus conference on gleason grading of prostatic carcinoma: definition of grading patterns and proposal for a new grading system;Epstein;Am J Surg Pathol,2016

3. EAU-ESTRO-SIOG guidelines on prostate cancer. Part 1: screening, diagnosis, and local treatment with curative intent;Mottet;Eur Urol,2017

4. 13-year outcomes following treatment for clinically localized prostate cancer in a population based cohort;Albertsen;J Urol,2007

5. The molecular taxonomy of primary prostate cancer;Cell,2015

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