Clarification and capture of high-concentration refold pools forE. coli-based therapeutics using expanded bed adsorption chromatography

Author:

Xu Xuankuo1,Hirpara Jeet1,Epting Kevin1,Jin Mi1,Ghose Sanchayita1,Rieble Siegfried1,Li Zheng Jian1

Affiliation:

1. Process Sciences Downstream; Bristol-Myers Squibb; East Syracuse NY 13057

Publisher

Wiley

Subject

Biotechnology

Reference79 articles.

1. Advances in refolding of protein produced in E;Lilie;coli. Curr Opin Biotechnol,1998

2. Refolding of recombinant proteins;Clark;Curr Opin Biotechnol.,1998

3. Preparative protein refolding;Middelberg;Trends Biotechnol,2002

4. Recombinant protein folding and misfolding in Escherichia coli;Baneyx;Nat Biotechnol,2004

5. Protein folding, misfolding, and aggregation: formation of inclusion bodies and aggresomes;Markossian;Biochemistry,2004

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