Aleukemic congenital leukemia cutis preceding monocytic leukemia with favorable outcome: A case report

Author:

Lo Presti Caroline1ORCID,Szymanski Gautier1,Lefebvre Christine1,Jacob Marie‐Christine2ORCID,Mossuz Pascal1,Gil Hugo3

Affiliation:

1. Department of Biological Hematology Grenoble Alpes University Hospital Grenoble France

2. Department of Immunology Grenoble Alpes University Hospital Grenoble France

3. Department of Anatomo‐Cytopathology Grenoble Alpes University Hospital Grenoble France

Abstract

AbstractA newborn girl had typical “blueberry muffin” skin lesions, which shows histopathologic features of monocytic leukemia cutis. The systemic leukemia was demonstrated after one month of life. She was treated by chemotherapy, including induction and three consolidation cures, according to the ELAM02 protocol, which led to complete remission. This case report with congenital form of AML5 cutaneous localization, preceding systemic involvement, with a 5‐year follow‐up and positive outcome is remarkable.

Publisher

Wiley

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