Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice

Author:

Hartmann Phillipp12,Hochrath Katrin1,Horvath Angela13,Chen Peng1,Seebauer Caroline T.1,Llorente Cristina14,Wang Lirui14,Alnouti Yazen5,Fouts Derrick E.6,Stärkel Peter7,Loomba Rohit1,Coulter Sally8,Liddle Christopher8,Yu Ruth T.9,Ling Lei10,Rossi Stephen J.10,DePaoli Alex M.10,Downes Michael9,Evans Ronald M.911,Brenner David A.1,Schnabl Bernd14

Affiliation:

1. Department of Medicine; University of California San Diego; La Jolla

2. Department of Pediatrics; University of California San Diego; La Jolla CA

3. Department of Gastroenterology and Hepatology; Medical University of Graz; Graz Austria

4. Department of Medicine; VA San Diego Healthcare System; San Diego CA

5. Department of Pharmaceutical Sciences; University of Nebraska Medical Center; Omaha NE

6. J. Craig Venter Institute; Rockville MD

7. St. Luc University Hospital; Université Catholique de Louvain; Brussels Belgium

8. Storr Liver Centre, Westmead Institute for Medical Research and Sydney Medical School; University of Sydney; Sydney Australia

9. Gene Expression Laboratory; Salk Institute for Biological Studies; La Jolla CA

10. NGM Bio; South San Francisco CA

11. Howard Hughes Medical Institute; Salk Institute for Biological Studies; La Jolla CA

Funder

Deutsche Forschungsgemeinschaft

NIH

Biomedical Laboratory Research and Development, VA Office of Research and Development

Publisher

Wiley

Subject

Hepatology

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