1. Unit for Drug Discovery, Department of Parasitology, Institute of Biomedical SciencesUniversity of São Paulo Avenida Professor Lineu Prestes 1374, São Paulo São Paulo 05508‐000 Brazil
2. Institute for Medical Informatics, Statistics and Epidemiology, Medical FacultyUniversity Leipzig D‐04107 Härtelstraße 16‐18, Leipzig Germany
3. Department of Biochemistry, Institute of ChemistryUniversity of São Paulo Avenida Professor Lineu Prestes 748, São Paulo São Paulo 05508‐900 Brazil
4. Structural Biology Unit, Department of Pharmacy, Faculty of Science and EngineeringUniversity of Groningen 9713AV Antonius Deusinglaan 1, AV Groningen The Netherlands