Small‐molecule‐mediated chemical knock‐down of MuRF1/MuRF2 and attenuation of diaphragm dysfunction in chronic heart failure

Author:

Adams Volker1ORCID,Bowen T. Scott2,Werner Sarah3,Barthel Peggy1,Amberger Christina3,Konzer Anne45,Graumann Johannes45,Sehr Peter6,Lewis Joe6,Provaznik Jan6,Benes Vladimir6,Büttner Petra3,Gasch Alexander7,Mangner Norman1,Witt Christian C.7,Labeit Dittmar78,Linke Axel1,Labeit Siegfried78

Affiliation:

1. Laboratory of Molecular and Experimental CardiologyTU Dresden, Heart Center Dresden Dresden Germany

2. School of Biomedical SciencesUniversity of Leeds Leeds UK

3. University Clinic of CardiologyHeart Center Leipzig Leipzig Germany

4. Scientific Service Group Biomolecular Mass SpectrometryMax Planck Institute for Heart and Lung Research Bad Nauheim Germany

5. German Centre for Cardiovascular Research (DZHK), Partner Site Rhine‐Main Rhine‐Main Germany

6. European Molecular Biology Laboratory Heidelberg Germany

7. Medical Faculty Mannheim, University of Heidelberg Heidelberg Germany

8. Myomedix GmbH Neckargemünd Germany

Funder

Horizon 2020

Fondation Leducq

Publisher

Wiley

Subject

Physiology (medical),Orthopedics and Sports Medicine

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