Autocrine activin A signalling in ovarian cancer cells regulates secretion of interleukin 6, autophagy, and cachexia-Reference-Cited by-同舟云学术

Autocrine activin A signalling in ovarian cancer cells regulates secretion of interleukin 6, autophagy, and cachexia

Published:2019-08-21 Issue:1 Volume:11 Page:195-207
ISSN:2190-5991
Container-title:Journal of Cachexia, Sarcopenia and Muscle
language:en
Short-container-title:Journal of Cachexia, Sarcopenia and Muscle

Author:

Pettersen Kristine¹²,Andersen Sonja¹²,Veen Anna²,Nonstad Unni²,Hatakeyama Shinji³,Lambert Christian³,Lach‐Trifilieff Estelle³,Moestue Siver⁴,Kim Jana⁴,Grønberg Bjørn Henning⁵⁶,Schilb Alain³,Jacobi Carsten³,Bjørkøy Geir¹²^ORCID

Affiliation:

1. Department of Biomedical Laboratory Science, Faculty of Natural Sciences NTNU‐Norwegian University of Science and Technology Trondheim Norway

2. Centre of Molecular Inflammation Research, Department of Clinical and Molecular Medicine NTNU‐Norwegian University of Science and Technology Trondheim Norway

3. Novartis Institutes for BioMedical Research Basel, Musculoskeletal Disease Area Novartis Pharma AG Basel Switzerland

4. Department of Circulation and Medical Imaging, Faculty of Medicine NTNU‐Norwegian University of Science and Technology Trondheim Norway

5. Department of Cancer Research and Molecular Medicine NTNU‐Norwegian University of Science and Technology Trondheim Norway

6. Clinic of Oncology St. Olavs Hospital ‐ Trondheim University Hospital Trondheim Norway

Funder

The Research Council of Norway

The Norwegian Cancer Society

Publisher

Wiley

Subject

Physiology (medical),Orthopedics and Sports Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcsm.12489

Reference56 articles.

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3. Elevated expression of activins promotes muscle wasting and cachexia

4. Development of cancer cachexia-like syndrome and adrenal tumors in inhibin-deficient mice.

5. Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival

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