Enhancement of adriamycin cytotoxicity by sodium butyrate involves hTERT downmodulation-mediated apoptosis in human uterine cancer cells

Author:

Yu Meng1,Kong Hong2,Zhao Yan3,Sun Xuefei4,Zheng Zhihong1,Yang Chunming5,Zhu Yuyan5

Affiliation:

1. Key Laboratory of Transgenetic Animal Research; Liaoning Province; Department of Laboratory Animal; China Medical University; Shenyang China

2. Department of Clinical Laboratory; Shengjing Hospital of China Medical University; Shenyang China

3. Department of Gynecology; Shengjing Hospital of China Medical University; Shenyang China

4. Department of Pharmaceutical Toxicology; School of Pharmaceutical Sciences; China Medical University; Shenyang China

5. Department of Urology; First Affiliated Hospital of China Medical University; Shenyang China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Liaoning Province

Scientific Research Foundation for Doctoral Program of Liaoning Province of China

New Teacher Fund for Doctor Station by Ministry of Education of China

Research Foundation of Shenyang City Science and Technology Bureau

Publisher

Wiley

Subject

Cancer Research,Molecular Biology

Reference25 articles.

1. Cancer statistics, 2010;Jemal;CA Cancer J Clin,2010

2. Endometrial carcinoma: A review of chemotherapy, drug resistance, and the search for new agents;Moxley;Oncologist,2010

3. Telomerase: A potential therapeutic target for cancer;Fletcher;Expert Opin Ther Targets,2005

4. Telomeres and telomerase in cancer;Artandi;Carcinogenesis,2010

5. Quantitative telomerase activity in malignant, benign and normal gynecological tissues;Saygan-Karamürsel;Eur J Gynaecol Oncol,2005

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