Fibronectin splice variation in human knee cartilage, meniscus and synovial membrane: Observations in osteoarthritic knee

Author:

Scanzello Carla R.1,Markova Dessislava Z.2,Chee Ana3,Xiu Yan4,Adams Sherrill L.5,Anderson Greg2,Zgonis Miltiadis4,Qin Ling4,An Howard S.3,Zhang Yejia36

Affiliation:

1. Division of Rheumatology; Philadelphia Veterans Affairs Medical Center; Perelman School of Medicine; University of Pennsylvania; Philadelphia Pennsylvania

2. Department of Orthopedic Surgery; Thomas Jefferson University; Philadelphia Pennsylvania

3. Department of Orthopedic Surgery; Rush University Medical Center; Chicago Illinois

4. Department of Orthopedic Surgery; Perelman School of Medicine; University of Pennsylvania; Philadelphia Pennsylvania

5. Department of Biochemistry; School of Dental Medicine; University of Pennsylvania; Philadelphia Pennsylvania

6. Philadelphia Veterans Affairs Medical Center, and Department of Physical Medicine and Rehabilitation; Perelman School of Medicine; University of Pennsylvania; Philadelphia Pennsylvania

Funder

National Institute of Child Health and Human Development

National Institute of Arthritis, Musculoskeletal and Skin Diseases

NIH

Publisher

Wiley

Subject

Orthopedics and Sports Medicine

Reference38 articles.

1. Osteoarthritis: a disease of the joint as an organ;Loeser;Arthritis Rheum,2012

2. Fibronectins, their fibrillogenesis, and in vivo functions;Schwarzbauer;Cold Spring Harb Perspect Biol,2011

3. The alternative splicing of fibronectin pre-mRNA is altered during aging and in response to growth factors;Magnuson;J Biol Chem,1991

4. Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan;Muro;J Cell Biol,2003

5. The extra-domain A of fibronectin is a vascular marker of solid tumors and metastases;Rybak;Cancer Res,2007

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