Development of a Generic Physiologically‐Based Pharmacokinetic Model for Lactation and Prediction of Maternal and Infant Exposure to Ondansetron via Breast Milk

Author:

Job Kathleen M.1,Dallmann André2,Parry Samuel3,Saade George4,Haas David M.5,Hughes Brenna6,Berens Pamela7,Chen Jia‐Yu8,Fu Christina8,Humphrey Kelsey8,Hornik Christoph9,Balevic Stephen9,Zimmerman Kanecia9,Watt Kevin1

Affiliation:

1. Division of Clinical Pharmacology Department of Pediatrics The University of Utah Salt Lake City Utah USA

2. Pharmacometrics/Modeling & Simulation Research & Development Bayer AG Leverkusen Germany

3. Division of Maternal‐Fetal Medicine Perelman School of Medicine of the University of Pennsylvania Philadelphia Pennsylvania USA

4. University of Texas Medical Branch–Galveston Galveston Texas USA

5. Indiana University School of Medicine Indianapolis Indiana USA

6. Department of Obstetrics and Gynecology Duke University Durham North Carolina USA

7. McGovern Medical School The University of Texas Health Science Center at Houston (UTHealth) Houston Texas USA

8. The Emmes Company, LLC Rockville Maryland USA

9. Duke Clinical Research Institute Duke University Durham North Carolina USA

Funder

National Institute of Child Health and Human Development

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

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