Patient‐reported predictors of postdischarge mortality after cardiac hospitalization

Author:

Nair Devika12ORCID,Schildcrout Jonathan S.3,Shi Yaping3,Trochez Ricardo3ORCID,Nwosu Sam3,Bell Susan P.4,Mixon Amanda S.56,Welch Sarah A.67,Goggins Kathryn25,Bachmann Justin M.48,Vasilevskis Eduard E.9,Cavanaugh Kerri L.12,Rothman Russell L.10,Kripalani Sunil B.2511ORCID

Affiliation:

1. Department of Medicine, Division of Nephrology and Hypertension Vanderbilt University Medical Center Nashville Tennessee USA

2. Vanderbilt Center for Health Services Research Vanderbilt University Medical Center Nashville Tennessee USA

3. Department of Biostatistics Vanderbilt University Medical Center Nashville Tennessee USA

4. Department of Medicine, Division of Cardiovascular Medicine Vanderbilt University Medical Center Nashville Tennessee USA

5. Section of Hospital Medicine, Division of General Internal Medicine and Public Health, Department of Medicine Vanderbilt University Medical Center Nashville Tennessee USA

6. Department of Veterans Affairs Geriatric Research Education and Clinical Center (GRECC), Tennessee Valley Healthcare System Nashville Tennessee USA

7. Department of Physical Medicine and Rehabilitation Vanderbilt University Medical Center Nashville Tennessee USA

8. Department of Biomedical Informatics Vanderbilt University Medical Center Nashville Tennessee USA

9. Division of Hospital Medicine University of Wisconsin Madison Wisconsin USA

10. Institute of Medicine and Public Health Vanderbilt University Medical Center Nashville Tennessee USA

11. Center for Clinical Quality and Implementation Research VUMC Nashville Tennessee USA

Abstract

AbstractBackgroundAdults hospitalized for cardiovascular events are at high risk for postdischarge mortality. Screening of psychosocial risk is prioritized by the Joint Commission. We tested whether key patient‐reported psychosocial and behavioral measures could predict posthospitalization mortality in a cohort of adults hospitalized for a cardiovascular event.MethodsWe conducted a prospective cohort study to test the prognostic utility of validated patient‐reported measures, including health literacy, social support, health behaviors and disease management, and socioeconomic status. Cox survival analyses of mortality were conducted over a median of 3.5 years.ResultsAmong 2977 adults hospitalized for either acute coronary syndrome or acute decompensated heart failure, the mean age was 53 years, and 60% were male. After adjusting for demographic, clinical, and other psychosocial factors, mortality risk was greatest among patients who reported being unemployed (hazard ratio [HR]: 1.99, 95% confidence interval [CI]): 1.30–3.06), retired (HR: 2.14, 95% CI: 1.60–2.87), or unable to work due to disability (HR: 2.36, 95% CI: 1.73–3.21), as compared to those who were employed. Patient‐reported perceived health competence (PHCS‐2) and exercise frequency were also associated with mortality risk after adjusting for all other variables (HR: 0.86, 95% CI: 0.73–1.00 per four‐point increase in PHCS‐2; HR: 0.86, 95% CI: 0.77–0.96 per 3‐day increase in exercise frequency, respectively).ConclusionsPatient‐reported measures of employment status, perceived health competence, and exercise frequency independently predict mortality after a cardiac hospitalization. Incorporating these brief, valid measures into hospital‐based screening may help with prognostication and targeting patients for resources during post‐discharge transitions of care.

Funder

National Heart, Lung, and Blood Institute

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

Wiley

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