Development of a high-throughput genotoxicity assay using Umu test strains expressing human cytochrome P450s and NADPH-P450 reductase and bacterial O -acetyltransferase-Reference-Cited by-同舟云学术

Development of a high-throughput genotoxicity assay using Umu test strains expressing human cytochrome P450s and NADPH-P450 reductase and bacterial O -acetyltransferase

Published:2017-04-24 Issue:4 Volume:58 Page:209-216
ISSN:0893-6692
Container-title:Environmental and Molecular Mutagenesis
language:en
Short-container-title:Environ. Mol. Mutagen.

Author:

Hori Hisako¹,Hirata Daisuke²,Fujii Wataru¹,Oda Yoshimitsu³

Affiliation:

1. Safety Science Institute, Suntory MONOZUKURI Expert Limited; Seika-cho Soraku-gun Kyoto Japan

2. Protein Purify Co. Ltd; Magarisawa-cho Isesaki-city Gunma Japan

3. Institute of Life and Environmental Sciences, Osaka Shin-Ai College; Tsurumi-ku Japan

Funder

Japan Health Science Foundation

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Genetics (clinical),Epidemiology

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3. Development of a new genotoxicity test system with Salmonella typhimurium OY1001/1A2 expressing human CYP1A2 and NADPH-P450 reductase;Aryal;Mutat Res,1999

4. Use of genetically engineered Salmonella typhimurium OY1002/1A2 strain coexpressing human cytochrome P450 1A2 and NADPH-cytochrome P450 reductase and bacterial O-acetyltransferase in SOS/umu assay;Aryal;Environ Mol Mutagen,2000

5. Hydroxymethyl-substituted furans: Mutagenicity in Salmonella typhimurium strains engineered for expression of various human and rodent sulphotransferases;Glatt;Mutagenesis,2012

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