T-cell-receptor engagement and tumor ICAM-1 up-regulation are required to by-pass low susceptibility of melanoma cells to autologous CTL-mediated lysis

Author:

Anichini Andrea,Mortarini Roberta,Parmiani Giorgio,Alberti Saverio,Mantovani Alberto

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference23 articles.

1. Distinct forms of both α and β subunits are present in human Ia molecular pool;Accolla;Proc. Nat. Acad. Sci. (Wash.),1981

2. Cytotoxic T lymphocyte clones from peripheral blood and from tumor site detect intratumor heterogeneity of melanoma cells. Analysis of specificity and mechanisms of interaction;Anichini;J. Immunol.,1989

3. β1 Integrins on melanoma clones regulate the interaction with autologous cytotoxic T cell clones;Anichini;J. Immunother.,1992

4. Human melanoma cells with high susceptibility to cell-mediated lysis can be identified on the basis of ICAM-1 phenotype, VLA profile and invasive ability;Anichini;Int. J. Cancer,1990

5. ICAM-1− melanoma cells are relatively resistant to CD3-mediated T-cell lysis;Braakman;Int. J. Cancer,1990

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