Risk of multiple myeloma is associated with polymorphisms within telomerase genes and telomere length

Author:

Campa Daniele1,Martino Alessandro2,Varkonyi Judit3,Lesueur Fabienne4,Jamroziak Krzysztof5,Landi Stefano6,Jurczyszyn Artur7,Marques Herlander89,Andersen Vibeke1011,Jurado Manuel1213,Brenner Hermann1415,Petrini Mario16,Vogel Ulla17,García-Sanz Ramón18,Buda Gabriele16,Gemignani Federica6,Ríos Rafael1213,Vangsted Annette Juul19,Dumontet Charles20,Martínez-López Joaquín21,Moreno María José22,Stępień Anna23,Wątek Marzena24,Moreno Victor25,Dieffenbach Aida Karina1415,Rossi Anna Maria6,Butterbach Katja14,Jacobsen Svend E. Hove26,Goldschmidt Hartmut27,Sainz Juan1213,Hillengass Jens27,Orciuolo Enrico16,Dudziński Marek28,Weinhold Niels27,Reis Rui Manuel8929,Canzian Federico2

Affiliation:

1. Division of Cancer Epidemiology; German Cancer Research Center (DKFZ); Heidelberg Germany

2. Genomic Epidemiology Group; German Cancer Research Center (DKFZ); Heidelberg Germany

3. Department of Internal Medicine; Semmelweis University; Budapest Hungary

4. Genetic Epidemiology of Cancer Team, INSERM, U900; Institut Curie; Mines ParisTech Paris France

5. Department of Hematology; Medical University of Łodz; Łodz Poland

6. Department of Biology; University of Pisa; Pisa Italy

7. Department of Hematology; Cracow University Hospital; Cracow Poland

8. Life and Health Sciences Research Institute; University of Minho; Braga Portugal

9. ICVS/3B's-PT Government Associate Laboratory, University of Minho; Braga/Guimarães Portugal

10. Organ Center; Hospital of Southern Jutland; Aabenraa Denmark

11. Institute of Regional Health Research, Faculty of Health Sciences; University of Southern Denmark; Odense C Denmark

12. Genomic Oncology Area, GENYO, Centre for Genomics and Oncological Research; Pfizer/University of Granada/Andalusian Regional Government; Granada Spain

13. Hematology Department; Virgen de las Nieves University Hospital; Granada Spain

14. Division of Clinical Epidemiology and Aging Research; German Cancer Research Center (DKFZ); Heidelberg Germany

15. German Cancer Consortium (DKTK); Heidelberg Germany

16. UO Hematology, Department of Internal and Experimental Medicine; University of Pisa; Pisa Italy

17. National Research Centre for the Working Environment; Copenhagen Denmark

18. Department of Hematology; University Hospital of Salamanca; Salamanca Spain

19. Department of Hematology; Roskilde Hospital, Copenhagen University; Roskilde Denmark

20. INSERM UMR 1052/CNRS 5286; Université Claude Bernard Lyon I; Lyon France

21. Department of Hematology; Hospital Universitario Doce de Octubre; Madrid Spain

22. Department of Hematology; Morales Meseguer General University Hospital; Murcia Spain

23. Laboratory of Clinical and Transplant Immunology and Genetics; Copernicus Memorial Hospital; Łodz Poland

24. Hematology Clinic; Holycross Cancer Center; Kielce Poland

25. Programme of Cancer Prevention and Unit of Biomarkers and Susceptibility; IDIBELL-Catalan Institute of Oncology and University of Barcelona; Barcelona Spain

26. Clinic of Immunology, Laboratory Center; Hospital of Southern Jutland; Sønderborg Denmark

27. Department of Internal Medicine V; University of Heidelberg; Heidelberg Germany

28. Division of Hematology; Rzeszow Regional Hospital; Rzeszow Poland

29. Molecular Oncology Research Center; Barretos Cancer Hospital; Barretos Brazil

Funder

Polish Ministry of Science and Higher Education

Research Fund at Region Sjaelland, DK; Baden-Württemberg State Ministry of Science, Research and Arts; CRIS Foundation

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference47 articles.

1. Multiple myeloma;Raab;Lancet,2009

2. Genetics and molecular epidemiology of multiple myeloma: the rationale for the IMMEnSE consortium (review);Martino;Int J Oncol,2012

3. Familial risks and temporal incidence trends of multiple myeloma;Altieri;Eur J Cancer,2006

4. Patterns of monoclonal gammopathy of undetermined significance and multiple myeloma in various ethnic/racial groups: support for genetic factors in pathogenesis;Landgren;Leukemia,2009

5. Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk;Broderick;Nat Genet,2012

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