Optimization and scale-up of oligonucleotide synthesis in packed bed reactors using computational fluid dynamics modeling-Reference-Cited by-同舟云学术

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Optimization and scale-up of oligonucleotide synthesis in packed bed reactors using computational fluid dynamics modeling

Published:2014-08-08 Issue:5 Volume:30 Page:1048-1056
ISSN:8756-7938
Container-title:Biotechnology Progress
language:en
Short-container-title:Biotechnol Progress

Author:

Wolfrum Christian¹,Josten Andre²,Götz Peter³

Affiliation:

1. Eckart GmbH Werk Wackersdorf; Boschstraße 1 92442 Wackersdorf Germany

2. Identif GmbH, Ulrich-Schalk-Str. 3, 91056 Erlangen; Germany

3. Bioprocess Engineering; Beuth University of Applied Sciences; Seestrasse 64 13347 Berlin Germany

Publisher

Wiley

Subject

Biotechnology

Reference26 articles.

1. Antisense oligonucleotides;De Mesmaeker;Acc Chem. Res,1995

2. Deoxynucleoside phosphoramidites-a new class of key intermediates for deoxypolynucleotide synthesis;Beaucage;Tetrahedron Lett,1981

3. Large scale synthesis of oligonucleotides via phosphoramidite nucleosides and a high-loaded polystyrene support;Wright;Tetrahedron Lett,1993

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