Immunodominance and functional alterations of tumor‐associated antigen‐specific CD8 + T‐cell responses in hepatocellular carcinoma

Author:

Flecken Tobias123,Schmidt Nathalie1,Hild Sandra1,Gostick Emma4,Drognitz Oliver5,Zeiser Robert6,Schemmer Peter7,Bruns Helge7,Eiermann Thomas8,Price David A.4,Blum Hubert E.1,Neumann‐Haefelin Christoph1,Thimme Robert1

Affiliation:

1. Department of Internal Medicine IIUniversity Hospital FreiburgFreiburg Germany

2. Spemann Graduate School of Biology and Medicine (SGBM)Albert‐Ludwigs‐UniversityFreiburg Germany

3. Faculty of BiologyAlbert‐Ludwigs‐UniversityFreiburg Germany

4. Institute of Infection and ImmunityCardiff University School of MedicineCardiff UK

5. Department of SurgeryUniversity Hospital FreiburgFreiburg Germany

6. Department of Internal Medicine IUniversity Hospital FreiburgFreiburg Germany

7. Department of General and Transplant SurgeryRuprecht‐Karls UniversityHeidelberg Germany

8. Department of Transfusion MedicineUniversity Hospital Hamburg‐EppendorfHamburg Germany

Funder

Wellcome Trust

Publisher

Wiley

Subject

Hepatology

Reference27 articles.

1. Hepatocellular Carcinoma

2. Cancer immunotherapy comes of age

3. Vascular adhesion protein‐1 and ICAM‐1 support the adhesion of tumor‐infiltrating lymphocytes to tumor endothelium in human hepatocellular carcinoma;Yoong KF;J Immunol,1998

4. Clinicopathological study on hepatocellular carcinoma with lymphocytic infiltration

5. Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trial

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