Prospective CYP2C19 ‐Guided Voriconazole Prophylaxis in Patients With Neutropenic Acute Myeloid Leukemia Reduces the Incidence of Subtherapeutic Antifungal Plasma Concentrations

Author:

Hicks J. Kevin1ORCID,Quilitz Rod E.2,Komrokji Rami S.3,Kubal Timothy E.3,Lancet Jeffrey E.3,Pasikhova Yanina2,Qin Dahui4,So Wonhee2,Caceres Gisela4,Kelly Kerry5,Salchert Yasmina S.4,Shahbazian Kevin1,Abbas‐Aghababazadeh Farnoosh6,Fridley Brooke L.6,Velez Ana P.7,McLeod Howard L.1ORCID,Greene John N.7

Affiliation:

1. Department of Individualized Cancer Management H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA

2. Department of Pharmacy H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA

3. Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA

4. Department of Pathology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA

5. Department of Clinical Informatics H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA

6. Department of Biostatistics and Bioinformatics H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA

7. Department of Infectious Disease H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference33 articles.

1. The epidemiology of fungal infections in patients with hematologic malignancies: the SEIFEM‐2004 study;Pagano L.;Haematologica,2006

2. Comparing the safety and efficacy of voriconazole versus posaconazole in the prevention of invasive fungal infections in high-risk patients with hematological malignancies

3. Posaconazole vs. Fluconazole or Itraconazole Prophylaxis in Patients with Neutropenia

4. Evaluation of the Practice of Antifungal Prophylaxis Use in Patients With Newly Diagnosed Acute Myeloid Leukemia: Results From the SEIFEM 2010-B Registry

5. European guidelines for primary antifungal prophylaxis in adult haematology patients: summary of the updated recommendations from the European Conference on Infections in Leukaemia;Maertens J.A.;J. Antimicrob. Chemother.,2018

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