One Year of Abaloparatide, a Selective Activator of the PTH1 Receptor, Increased Bone Formation and Bone Mass in Osteopenic Ovariectomized Rats Without Increasing Bone Resorption-Reference-Cited by-同舟云学术

One Year of Abaloparatide, a Selective Activator of the PTH1 Receptor, Increased Bone Formation and Bone Mass in Osteopenic Ovariectomized Rats Without Increasing Bone Resorption

Published:2016-10-17 Issue:1 Volume:32 Page:24-33
ISSN:0884-0431
Container-title:Journal of Bone and Mineral Research
language:en
Short-container-title:J Bone Miner Res

Author:

Varela Aurore¹,Chouinard Luc¹,Lesage Elisabeth¹,Smith Susan Y¹,Hattersley Gary²

Affiliation:

1. Charles River Laboratories; Montreal Canada

2. Radius Health Inc.; Waltham MA, USA

Funder

Radius Health

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jbmr.3003/fullpdf

Reference49 articles.

1. Effects of abaloparatide, a human parathyroid hormone-related peptide analog, on bone mineral density in postmenopausal women with osteoporosis;Leder;J Clin Endocrinol Metab,2015

2. Effect of abaloparatide vs placebo on new vertebral fractures in postmenopausal women with osteoporosis: a randomized clinical trial;Miller;JAMA,2016

3. ClinicalTrials.gov 2015 https://clinicaltrials.gov/ct2/show/NCT01657162?term=abaloparatide&rank=3

4. Six month daily administration of parathyroid hormone and parathyroid hormone-related protein peptides to adult ovariectomized rats markedly enhances bone mass and biomechanical properties: a comparison of human parathyroid hormone 1-34, parathyroid hormone-related protein 1-36, and SDZ-parathyroid hormone 893;Stewart;J Bone Miner Res,2000

5. Daily treatment of aged ovariectomized rats with human parathyroid hormone (1-84) for 12 months reverses bone loss and enhances trabecular and cortical bone strength;Fox;Calcif Tissue Int,2006

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