Use of Arabinonucleosides for Development and Implementation of a Novel 2′‐ <i>O</i> ‐Protecting Group for Efficient Solid‐Phase Synthesis and 2′‐ <i>O</i> ‐Deprotection of RNA Sequences-Reference-Cited by-同舟云学术

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Use of Arabinonucleosides for Development and Implementation of a Novel 2′‐ O ‐Protecting Group for Efficient Solid‐Phase Synthesis and 2′‐ O ‐Deprotection of RNA Sequences

Published:2022-01 Issue:1 Volume:2 Page:
ISSN:2691-1299
Container-title:Current Protocols
language:en
Short-container-title:Current Protocols

Author:

Takahashi Mayumi¹,Cawrse Brian M.¹,Grajkowski Andrzej¹,Beaucage Serge L.¹

Affiliation:

1. Laboratory of Biological Chemistry Center for Drug Evaluation and Research, Food and Drug Administration Silver Spring Maryland

Publisher

Wiley

Subject

Medical Laboratory Technology,Health Informatics,General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpz1.346

Reference48 articles.

1. Recent Advances in the Chemical Synthesis of RNA

2. Use of the 1-(2-fluorophenyl)-4-methoxypiperidin-4-yl (Fpmp) and related protecting groups in oligoribonucleotide synthesis: stability of internucleotide linkages to aqueous acid

3. Safety of antisense oligonucleotide and siRNA-based therapeutics

4. The 2-Cyano-2,2-dimethylethanimine-N-oxymethyl Group for the 2′-Hydroxyl Protection of Ribonucleosides in the Solid-Phase Synthesis of RNA Sequences

5. 2′‐Hydroxy Protection of Ribonucleosides as 2‐Cyano‐2,2‐Dimethylethanimine‐ N ‐Oxymethyl Ethers in Solid‐Phase Synthesis of RNA Sequences

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